Research
Macro partitioning
High intake of red meat and saturated fat is associated with an increased risk of colon cancer, prostate cancer, and myocardial infarction.
Limiting red meat and saturated fat intake is associated with lower risks of colon, prostate, and heart disease. This aligns with standard cardiovascular and cancer prevention guidelines.
GoodSupportsHIGH confidence
We also found that red meat intake was associated with an increased risk of colon cancer (17) and male diabetes (18). Saturated fat intake was associated with an increased risk of prostate cancer (19) and myocardial infarction but a decreased risk of stroke (20).
Why this rating
Consistent inverse associations with health outcomes across multiple endpoints in a large cohort.
Source
The JPHC Study: Design and Some Findings on the Typical Japanese Diet
Shoichiro Tsugane et al. · Japanese Journal of Clinical Oncology · 2014
DOI 10.1093/jjco/hyu096
cohort · n=140420Cited 384×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High consumption of soy and isoflavones is associated with a decreased risk of post-menopausal breast cancer and localized prostate cancer.Good
- High intake of fish and n-3 fatty acids is associated with a decreased risk of proximal colon cancer, liver cancer, and myocardial infarction.Good
- High salt and salted food intake is associated with an increased risk of stomach cancer and cardiovascular disease.Good
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →