Micronutrients & recovery
The kynurenine/tryptophan (Kyn/Trp) ratio in blood serves as a robust biomarker for the rate of physiological aging (inflammaging) and predicts age-related diseases and mortality.
You can monitor your Kyn/Trp ratio as a blood test to assess your biological aging rate and risk for age-related diseases. A higher ratio indicates increased inflammatory activity associated with aging. This is a diagnostic tool, not a treatment, but it helps identify who might benefit from lifestyle interventions targeting inflammation.
The Kyn/Trp ratio, measured in blood, is robustly associated with aging in humans... implies that the age-dependent increase in the Kyn/Trp ratio is not secondary to the onset of disease but rather represents a physiological age-related change.
Why this rating
Supported by multiple observational human studies cited in the review showing association with frailty, cognitive performance, and mortality.
Source
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
Freek J. H. Sorgdrager et al. · Frontiers in Immunology · 2019
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