Research
Micronutrients & recovery
Marine n-3 fatty acid supplementation (specifically EPA at 4g/day) reduces cardiovascular events in high-risk patients with elevated triglycerides, independent of statin therapy.
If you have high triglycerides and are at high cardiovascular risk, ask your doctor about high-dose EPA (4g/day). This specific intervention has been shown to significantly reduce heart attacks and strokes, even for those already taking statins.
StrongSupportsHIGH confidence
In REDUCE-IT, treatment of patients at elevated cardiovascular risk... with 4 g of EPA/day resulted in a 25% relative risk reduction... of the primary composite end point... It is noteworthy that these results were achieved on top of statin therapy, suggesting additive value of EPA.
Why this rating
Based on the REDUCE-IT trial, a large, landmark clinical trial.
Source
Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors
Katharina Lechner et al. · European Journal of Preventive Cardiology · 2019
narrative_reviewCited 360×
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