Energy balance
Weight loss interventions, including lifestyle changes and bariatric surgery, reduce blood pressure, glomerular hyperfiltration, and proteinuria in obese patients with CKD.
If you are overweight and have early kidney disease or diabetes, losing weight through diet and exercise can significantly lower your risk of developing kidney failure. This is achieved by reducing the workload on your kidneys. However, if you have advanced kidney disease, weight loss decisions must be made carefully with your doctor, as your body may need extra reserves to fight illness.
In a recent meta-analysis collating experimental studies in obese CKD patients, interventions aimed at reducing body weight showed coherent reductions in blood pressure, glomerular hyper-filtration and proteinuria.
Why this rating
Based on meta-analyses and post-hoc analyses, but the paper notes a 'paucity of high-level evidence intervention studies'.
Source
Obesity and kidney disease: Hidden consequences of the epidemic
Csaba P. Kövesdy et al. · Indian Journal of Nephrology · 2017
DOI 10.4103/ijn.ijn_61_17
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →