Research
Mixed
FMT can improve insulin sensitivity and increase butyrate-producing intestinal microbiota in patients with metabolic syndrome when lean donor stool is used.
If you have metabolic syndrome, FMT from lean donors might improve your insulin sensitivity and gut health, based on a small study. This is still experimental and not a standard treatment.
LimitedSupportsLOW confidence
Patients who received fecal microbiota infusion from lean male donors reported a marked increase in insulin sensitivity and levels of butyrate-producing intestinal microbiota after 6-week infusion, whereas no significant changes were seen in the control group.
Why this rating
Based on a single small RCT (18 patients).
Source
Fecal Microbiota Transplantation: Current Applications, Effectiveness, and Future Perspectives
Hyun Ho Choi et al. · Clinical Endoscopy · 2016
DOI 10.5946/ce.2015.117
narrative_reviewCited 323×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Fecal microbiota transplantation (FMT) is a highly effective treatment for recurrent Clostridium difficile infection (CDI), achieving significantly higher symptom resolution rates compared to standard antibiotic therapies alone.Good
- FMT shows promise in treating Inflammatory Bowel Disease (IBD), including Ulcerative Colitis (UC) and Crohn's Disease (CD), but efficacy is lower and more variable than in CDI, with clinical remission rates around 36-45% in systematic reviews.Moderate
Related findings · Mixed
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