Research
Micronutrients & recovery
Food fortification and thiamine supplementation are effective interventions for raising thiamine status and reducing infantile beriberi in high-risk regions, although trial data remains limited.
If you live in an area where rice is the main food source, check if it is fortified. If you are pregnant or breastfeeding, discuss thiamine supplementation with your healthcare provider to protect your baby's health.
ModerateSupportsMEDIUM confidence
Food fortification and maternal and/or infant thiamine supplementation have proven effective in raising thiamine status and reducing the incidence of infantile beriberi in regions where thiamine deficiency is prevalent, but trial data are limited.
Why this rating
The paper states trial data are limited, relying on proven effectiveness in specific contexts rather than large-scale RCTs.
Source
Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs
Kyly C. Whitfield et al. · Annals of the New York Academy of Sciences · 2018
DOI 10.1111/nyas.13919
narrative_reviewCited 319×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Thiamine (Vitamin B1) is an essential micronutrient required for energy metabolism, and its deficiency leads to severe clinical disorders like beriberi and Wernicke-Korsakoff syndrome, particularly in populations relying on polished rice or facing food insecurity.Good
- Subclinical thiamine deficiency in childhood may have lifelong neurodevelopmental consequences, necessitating urgent public health responses even in the absence of overt clinical symptoms.Moderate
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