Energy balance
Achieving a 5-10% body weight reduction through lifestyle modification (diet and physical activity) significantly improves serum liver enzymes, reduces hepatic steatosis, and can improve histological features of NASH.
Aim to lose 5-10% of your body weight through a combination of a balanced, calorie-controlled diet and regular moderate exercise (like walking). You do not need to achieve massive weight loss to see improvements in liver enzymes and fat content. Focus on sustainable lifestyle changes and behavioral strategies rather than drastic, short-term diets.
Based on available data, patients should optimally achieve a 5%-10% weight reduction... The usual management of NAFLD includes gradual weight reduction and increased physical activity (PA) leading to an improvement in serum liver enzymes, reduced hepatic fatty infiltration, and, in some cases, a reduced degree of hepatic inflammation and fibrosis.
Why this rating
Supported by multiple RCTs and observational studies, though the paper notes limitations regarding repeated liver biopsies in many studies.
Source
Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence
Shira Zelber‐Sagi · World Journal of Gastroenterology · 2011
DOI 10.3748/wjg.v17.i29.3377
More from this paper
- High consumption of sugar-sweetened beverages (specifically fructose-containing drinks) is positively associated with an increased risk of NAFLD and higher fibrosis stages, independent of total caloric intake and BMI.Good
- Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation (1000-2700 mg/day) significantly decreases serum liver enzymes (ALT, AST, GGT) and reduces liver fat in NAFLD patients.Moderate
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