Research

Micronutrients & recovery

Lower baseline circulating cysteine concentrations are significantly associated with a positive weight loss response to exenatide treatment.

Current research suggests that women with lower baseline levels of the amino acid cysteine may be more likely to respond to exenatide. This is an emerging biomarker finding and not yet a standard clinical test for predicting response.

ModerateSupportsMEDIUM confidence
We observed lower cysteine concentrations in the exenatide responder group (0.81 vs 0.48 p < 0.0001)
Megan Rodgers et al. · Frontiers in Endocrinology · 2021

Why this rating

Exploratory analysis with a small subset of subjects (n=36 high responders, n=28 low responders), underpowered for definitive conclusions.

Source

Weight Loss Outcomes Among Early High Responders to Exenatide Treatment: A Randomized, Placebo Controlled Study in Overweight and Obese Women

Megan Rodgers et al. · Frontiers in Endocrinology · 2021

rct · n=182Cited 23×
Read the paper

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