Research
Mixed
Blood-based inflammatory biomarkers (IL-6, TNF-α) are suitable for field testing using dry blood spot sampling, unlike DNA methylation-based biomarkers which require advanced laboratory processes.
For field studies, consider using dry blood spot sampling to measure IL-6 and TNF-α, as these can be collected remotely and analyzed, unlike DNA methylation which requires advanced lab processing.
GoodSupportsHIGH confidence
advancements in novel collection methods, such as dry blood spot sampling, means that IL-6 and TNF-α can be measured from samples collected in remote settings.
Why this rating
Based on expert consensus regarding suitability for field settings.
Source
An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies
Giorgia Perri et al. · The Journals of Gerontology Series A · 2024
DOI 10.1093/gerona/glae297
clinical_guideline · n=60Cited 21×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Expert consensus identifies 14 biomarkers of aging suitable for use as outcome measures in human intervention studies, spanning physiological, inflammatory, functional, and epigenetic domains.Good
- Functional and physiological biomarkers are more suitable for medium- and long-term interventions (≥3 months) than acute or short-term interventions (<3 months).Good
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