Research
Mixed
Adherence to a Mediterranean Diet may attenuate the negative cardiovascular effects associated with specific genetic polymorphisms, such as the T-allele of the TCF7L2 gene and the G-allele of the MLXIPL gene.
If you have a family history of heart disease or diabetes, adhering to a Mediterranean Diet may be particularly beneficial in mitigating your genetic risk. Consult a genetic counselor or doctor for personalized advice.
ModerateQualifiesMEDIUM confidence
Their results suggest that the adherence to the Mediterranean diet might attenuate the effect of this genetic predisposition [26]. ... The protective effects of the Mediterranean diet against cardiovascular risk were mainly evidenced in subject who presented higher adherence to this dietary approach.
Why this rating
Based on specific studies within the PREDIMED trial and other cohorts; requires genetic testing to identify the subgroup.
Source
Metabolic and Vascular Effect of the Mediterranean Diet
Antonino Tuttolomondo et al. · International Journal of Molecular Sciences · 2019
DOI 10.3390/ijms20194716
narrative_reviewCited 268×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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