Research

Micronutrients & recovery

High fructose consumption accelerates the development of metabolic syndrome and CKD progression by inducing oxidative stress, hyperuricemia, and inflammation, whereas glucose does not produce these specific adverse renal effects.

Limit high-fructose corn syrup and sucrose intake, especially from sugary drinks. Fructose uniquely stresses the kidneys by depleting ATP and increasing uric acid and oxidative stress. Switching to a low-fructose diet can reduce inflammation and blood pressure in CKD patients.

GoodSupportsHIGH confidence
there is strong evidence that fructose, but not glucose, accelerates the development of metabolic syndrome and the progression of CKD.
Alex Odermatt · American Journal of Physiology-Renal Physiology · 2011

Why this rating

Supported by multiple rodent studies and human observational studies linking high-sugar beverages to CKD and hyperuricemia.

Source

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

Alex Odermatt · American Journal of Physiology-Renal Physiology · 2011

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