Research
Micronutrients & recovery
Bioactive food components such as genistein, EGCG, sulforaphane, and curcumin can modify DNA methylation and histone acetylation, potentially acting as chemopreventive agents by reactivating silenced tumor suppressor genes.
Include foods rich in bioactive compounds (green tea, cruciferous vegetables, turmeric, soy) in your diet. While they may support healthy gene expression patterns, they are not substitutes for medical care or proven cancer treatments, and their potency is lower than pharmaceutical agents.
ModerateSupportsMEDIUM confidence
Genistein... interferes with subsequent regulatory processes leading to decreased methylation at the uncoupling protein 1 and synaptotagmin-like 1 promoters... EGCG... reactivates silenced tumour suppressor genes p21 and p16... Sulforaphane inhibits HDAC activity in vivo and suppresses tumorigenesis...
Why this rating
Based on in vitro and animal models; human clinical data for these specific epigenetic effects is limited or preliminary.
Source
Nutritional influences on epigenetics and age-related disease
Lara K Park et al. · Proceedings of The Nutrition Society · 2011
narrative_reviewCited 232×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →