Mixed
Higher habitual intake of anthocyanins is associated with a significantly lower risk of nonfatal myocardial infarction in men, with the protective effect being stronger in normotensive individuals.
For men looking to reduce their risk of nonfatal heart attacks, increasing habitual intake of anthocyanin-rich fruits (like blueberries, blackberries, cherries, and red grapes) is a viable strategy. The benefit appears most pronounced in men with normal blood pressure. While this won't necessarily prevent fatal heart attacks or strokes, it is a low-risk dietary addition that aligns with broader cardiovascular health goals.
after multivariate adjustment, a higher habitual intake of anthocyanins was associated with a 14% lower risk of nonfatal MI (HR: 0.87; 95% CI: 0.75, 1.00; P-trend = 0.098)... this association was stronger in normotensive participants (HR: 0.81; 95% CI: 0.69, 0.96; P-interaction = 0.03).
Why this rating
Large prospective cohort (n=43,880), long follow-up (24 years), rigorous adjustment for confounders, but observational design prevents causal inference.
Source
Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men,
Aedín Cassidy et al. · American Journal of Clinical Nutrition · 2016
DOI 10.3945/ajcn.116.133132
More from this paper
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →