Hormonal
Treatment with 0.6 mg/day of the long-acting GLP-1 derivative liraglutide for 8 weeks significantly improves glycemic control (reducing fasting glucose and HbA1c) in obese patients with type 2 diabetes without causing weight gain.
If you have type 2 diabetes and are obese, taking 0.6 mg of liraglutide once daily for at least 8 weeks will significantly lower your fasting blood sugar and HbA1c. However, do not expect to lose weight or change your energy expenditure in this timeframe; your weight will likely stay the same. This treatment is effective for blood sugar control without the weight gain often seen with other diabetes drugs.
Eight weeks of 0.6-mg liraglutide treatment significantly improved glycemic control without increasing weight in subjects with type 2 diabetes compared with those on placebo.
Why this rating
Randomized, double-blind, placebo-controlled trial, though limited by a short duration (8 weeks) and small sample size (n=33).
Source
The Effect of Liraglutide, a Long-Acting Glucagon-Like Peptide 1 Derivative, on Glycemic Control, Body Composition, and 24-h Energy Expenditure in Patients With Type 2 Diabetes
Helle Harder et al. · Diabetes Care · 2004
DOI 10.2337/diacare.27.8.1915
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