Research
Micronutrients & recovery
Elevated levels of branched-chain amino acids (BCAAs) and aromatic amino acids, along with altered lipid profiles (e.g., elevated palmitic acid), serve as consistent metabolomic signatures of obesity and insulin resistance.
If you have obesity, check your metabolic markers, specifically amino acids and fatty acids. Elevated BCAAs and certain fatty acids like palmitic acid are linked to insulin resistance. Monitoring these can help identify metabolic dysfunction early, even if your weight is stable.
GoodSupportsHIGH confidence
Elevated levels of branched-chain AAs (BCAAs) (leucine, isoleucine, and valine) and aromatic AAs (phenylalanine, tyrosine, tryptophan and methionine)... have been detected in both subjects with obesity and diabetes... Regarding lipid metabolites, the levels of some fatty acids (FAs), e.g., palmitic, palmitoleic, stearic, and oleic acids, and stearoyl carnitine are elevated in obese subjects.
Why this rating
Systematic review of multiple targeted and untargeted metabolomics studies.
Source
Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies
Óscar Daniel Rangel-Huerta et al. · Metabolomics · 2019
DOI 10.1007/s11306-019-1553-y
systematic_reviewCited 223×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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