Micronutrients & recovery
Selenium deficiency alters gut microbiota composition and function, leading to a phenotype that increases susceptibility to cancer, thyroid dysfunction, inflammatory bowel disease, and cardiovascular disorders.
Ensure adequate selenium intake through diet (e.g., Brazil nuts, seafood, meat) or supplementation if deficient, as this supports a healthy gut microbiota which protects against chronic diseases like cancer and cardiovascular disorders.
Selenium deficiency may result in a phenotype of gut microbiota that is more susceptible to cancer, thyroid dysfunctions, inflammatory bowel disease, and cardiovascular disorders.
Why this rating
Based on a comprehensive review of experimental studies and observational data linking Se status to microbiota and disease.
Source
Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
Rannapaula Lawrynhuk Urbano Ferreira et al. · Frontiers in Nutrition · 2021
DOI 10.3389/fnut.2021.685317
More from this paper
- In conditions of limited selenium supply, intestinal bacteria compete with the host for selenium, reducing host selenoprotein levels by two to three times.Good
- High-dose selenium supplementation (200 µg/day) as selenized yeast or L-selenomethionine has shown mixed results in cancer prevention trials, with some showing reduced risk and others showing no benefit or increased risk.Good
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