Research

Micronutrients & recovery

High-dose selenium supplementation (200 µg/day) as selenized yeast or L-selenomethionine has shown mixed results in cancer prevention trials, with some showing reduced risk and others showing no benefit or increased risk.

Selenium supplementation (200 µg/day) has shown mixed results in cancer prevention. It may be beneficial in some populations (e.g., those with low baseline selenium) but not others. Consult a healthcare provider for personalized advice.

GoodQualifiesHIGH confidence
The Nutritional Prevention of Cancer (NPC) trial showed the effectiveness of supplementing 200 µg/day of Se, as selenized yeast, in reducing the risk of prostate, lung, and colorectal cancers... Neither selenium nor vitamin E, alone or in combination, was able to prevent prostate cancer in this population (SELECT trial).
Rannapaula Lawrynhuk Urbano Ferreira et al. · Frontiers in Nutrition · 2021

Why this rating

Based on multiple large-scale clinical trials (NPC, SELECT).

Source

Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases

Rannapaula Lawrynhuk Urbano Ferreira et al. · Frontiers in Nutrition · 2021

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