Research
Energy balance
Skeletal muscle is a key metabolic tissue responsible for ~80% of postprandial glucose disposal, and its circadian disruption contributes to insulin resistance and metabolic syndrome.
Prioritize muscle-building activities and regular physical activity to improve your body's ability to handle glucose after meals. Since muscles handle most of your post-meal sugar, stronger muscles can help prevent insulin resistance and type 2 diabetes.
StrongSupportsVERY_HIGH confidence
As much as 80% of postprandial glucose is taken up by skeletal muscle... Decreased insulin sensitivity in skeletal muscle is involved in the onset of type 2 diabetes... altered muscle function can contribute to insulin resistance and metabolic syndrome
Why this rating
Supported by extensive human and animal literature cited in the paper (DeFronzo et al., Ferrannini et al.).
Source
Circadian Rhythms, the Molecular Clock, and Skeletal Muscle
Brianna D. Harfmann et al. · Journal of Biological Rhythms · 2014
DOI 10.1177/0748730414561638
narrative_reviewCited 207×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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