Research

Micronutrients & recovery

Nicotinamide mononucleotide (NMN) supplementation increases NAD+ levels in aged organisms, which reverses age-related declines in mitochondrial function, insulin sensitivity, and cognitive performance.

Current evidence for NMN's anti-aging benefits comes from animal studies showing improved metabolic and cognitive health. Human clinical trials are ongoing, but no efficacy data is yet available. Do not expect proven anti-aging results in humans until more clinical data is published.

ModerateSupportsMEDIUM confidence
NMN, as the precursor of NAD+, can slow down this process by elevating NAD+ levels in the body. A number of in vivo studies have indicated affirmative results of therapeutic effects for various age-induced complications with NMN supplementation.
Harshani Nadeeshani et al. · Journal of Advanced Research · 2021

Why this rating

Evidence is derived from multiple in vivo animal studies (mice, rats, worms, flies) but lacks robust human clinical trial data.

Source

Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns

Harshani Nadeeshani et al. · Journal of Advanced Research · 2021

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