Micronutrients & recovery
Nicotinamide mononucleotide (NMN) supplementation increases NAD+ levels in aged organisms, which reverses age-related declines in mitochondrial function, insulin sensitivity, and cognitive performance.
Current evidence for NMN's anti-aging benefits comes from animal studies showing improved metabolic and cognitive health. Human clinical trials are ongoing, but no efficacy data is yet available. Do not expect proven anti-aging results in humans until more clinical data is published.
NMN, as the precursor of NAD+, can slow down this process by elevating NAD+ levels in the body. A number of in vivo studies have indicated affirmative results of therapeutic effects for various age-induced complications with NMN supplementation.
Why this rating
Evidence is derived from multiple in vivo animal studies (mice, rats, worms, flies) but lacks robust human clinical trial data.
Source
Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
Harshani Nadeeshani et al. · Journal of Advanced Research · 2021
DOI 10.1016/j.jare.2021.08.003
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