Research
Micronutrients & recovery
NMN supplementation improves specific age-related physiological declines, including insulin sensitivity, vascular function, and cognitive performance, in aged animal models.
Animal studies show NMN can improve insulin sensitivity, blood vessel health, and memory in old age. However, these results have not been confirmed in humans. Wait for clinical trial results before expecting these specific benefits.
ModerateSupportsMEDIUM confidence
NMN administration could enhance NAD+ levels... insulin secretion, insulin sensitivity and lipid profile in age-induced type 2 diabetic mice... restored maximum carotid artery endothelium-dependent dilation... restored learning and cognition in AD model Wistar rats.
Why this rating
Consistent findings across multiple animal models (mice, rats, worms) for specific endpoints, but no human efficacy data.
Source
Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
Harshani Nadeeshani et al. · Journal of Advanced Research · 2021
DOI 10.1016/j.jare.2021.08.003
narrative_reviewCited 202×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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