Research

Mixed

There is inconclusive evidence that NMES prevents skeletal-muscle wasting (loss of muscle mass) in critically ill patients.

Do not assume NMES will stop muscle wasting (size loss) in ICU patients. While it helps maintain strength, the evidence for preserving actual muscle mass is mixed. Focus on NMES for its proven ability to maintain functional strength rather than expecting it to fully prevent atrophy.

ModerateQualifiesMEDIUM confidence
However, there is inconclusive evidence for its benefit in prevention of muscle wasting.
Nicola A. Maffiuletti et al. · BMC Medicine · 2013

Why this rating

Based on 4 studies, only 2 found positive outcomes for mass, with small-to-moderate effect sizes or no effect.

Source

Neuromuscular electrical stimulation for preventing skeletal-muscle weakness and wasting in critically ill patients: a systematic review

Nicola A. Maffiuletti et al. · BMC Medicine · 2013

DOI 10.1186/1741-7015-11-137

systematic_review · n=172Cited 195×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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