Research

Micronutrients & recovery

Polyphenols found in the Mediterranean Diet (e.g., from olive oil and red wine) reduce cancer risk by inhibiting inflammatory pathways (NF-κB, COX-2) and modulating signaling molecules (mTOR, sirtuins).

Consume polyphenol-rich foods like extra virgin olive oil, red wine (in moderation), and colorful fruits/vegetables. These contain compounds that help regulate inflammation and cell growth pathways, potentially lowering cancer risk.

ModerateSupportsMEDIUM confidence
Dietary polyphenols from olive oil (oleuropein, hydroxyltyrosol) and from red wine (resveratrol) were shown to modulate the eicosanoids pathway through the inhibition of cellular enzymes such as phospholipase A2 (PLA2), cyclooxygenase (COX-1 and COX-2) and lipoxigenase (LOX).
Rita Ostan et al. · Nutrients · 2015

Why this rating

Based on cellular and animal models; human intervention studies are mixed or inconclusive regarding specific polyphenol efficacy.

Source

Inflammaging and Cancer: A Challenge for the Mediterranean Diet

Rita Ostan et al. · Nutrients · 2015

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