Micronutrients & recovery
There is insufficient evidence to determine the benefit of vitamin D, calcium, or combined supplementation for preventing fractures in community-dwelling men and premenopausal women.
For men and premenopausal women, current research does not provide enough information to say whether vitamin D and calcium supplements prevent fractures. Because the evidence is insufficient and there are known risks (like kidney stones), these supplements are not recommended for primary fracture prevention in these groups.
The USPSTF found inadequate evidence to estimate the benefits of vitamin D, calcium, or combined supplementation to prevent fractures in community-dwelling men and premenopausal women.
Why this rating
Evidence is described as 'inadequate' or 'lacking', preventing a definitive conclusion.
Source
Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults
US Preventive Services Task Force et al. · JAMA · 2018
DOI 10.1001/jama.2018.3185
More from this paper
- Daily supplementation with 400 IU or less of vitamin D and 1000 mg or less of calcium provides no benefit for the primary prevention of fractures in community-dwelling, postmenopausal women.Good
- Supplementation with vitamin D and calcium increases the incidence of kidney stones in community-dwelling adults.Good
Related findings · Micronutrients & recovery
- Trans fats (industrial trans-fatty acids) are unequivocally harmful and should be completely avoided as they raise LDL-C, TGs, and Apo B while lowering HDL-C.Strong
- For menopausal women with osteoporosis, first-line pharmacologic therapies include alendronate, risedronate, zoledronic acid, and denosumab for the prevention of hip, nonvertebral, and vertebral fractures.Strong
- Folic acid fortification of flour prevents neural tube birth defects, and mandatory fortification is more effective than voluntary supplementation alone.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →