Research
Micronutrients & recovery
Circulating levels of alpha-linolenic acid (ALA), an intermediate-chain omega-3 from plant sources, are not significantly associated with prevalent subclinical infarcts or white matter grade, and dietary ALA intake shows no significant association with MRI findings.
While plant-based omega-3s (ALA) have other health benefits, this study suggests they may not offer the same brain-protective benefits as fish-derived omega-3s (DHA/EPA) regarding silent brain strokes and white matter health.
ModerateRefutesMEDIUM confidence
Phospholipid ALA content was not associated with prevalent subclinical or incident infarcts or white matter grade... dietary ALA was not significantly associated with any of the MRI findings, except for a cross-sectional association with white matter grade...
Why this rating
Observational data; the association with sulcal/ventricular grades was borderline and not supported by dietary intake analysis.
Source
Circulating Omega‐3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study
Jyrki K. Virtanen et al. · Journal of the American Heart Association · 2013
cohort · n=3660Cited 84×
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