Research
Micronutrients & recovery
Long-term use of single antioxidant supplements (Vitamin E, Beta-carotene) does not prevent cardiovascular disease and may increase the risk of certain adverse events.
Do not take single antioxidant supplements (like Vitamin E or Beta-Carotene) to prevent heart disease. Large studies show they do not work and may even be harmful. Focus on getting antioxidants from a healthy diet instead.
StrongRefutesVERY_HIGH confidence
However, results from large randomized controlled trials did not support long-term use of single antioxidant supplements for CVD prevention due to their null or even adverse effects on major cardiovascular events or cancer.
Why this rating
Based on large-scale, long-term randomized controlled trials (RCTs), the gold standard for evidence.
Source
Plasma and Dietary Antioxidant Status as Cardiovascular Disease Risk Factors: A Review of Human Studies
Ying Wang et al. · Nutrients · 2013
DOI 10.3390/nu5082969
narrative_reviewCited 189×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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