Research

Mixed

Probiotics (specifically Lactobacillus strains) and prebiotics (fructooligosaccharides) can mitigate fructose-induced NAFLD by restoring gut barrier integrity and reducing inflammation.

If you consume high amounts of sugar, consider adding specific probiotics (like Lactobacillus strains) and prebiotics (like FOS). These help repair the gut barrier, preventing liver inflammation caused by sugar-induced gut leakage.

GoodSupportsHIGH confidence
Nutritional supplementation with probiotics and preobiotics impacting composition of gut microbiota can improve the outcome of NAFLD... Treatment with Lactobacillus rhamnosus GG... restored the duodenal tight junction proteins... attenuated activation of TLR4 signaling.
Jessica Lambertz et al. · Frontiers in Immunology · 2017

Why this rating

Supported by multiple animal studies cited in Table 1 showing specific strain efficacy.

Source

Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease

Jessica Lambertz et al. · Frontiers in Immunology · 2017

DOI 10.3389/fimmu.2017.01159

narrative_reviewCited 183×
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DOI resolved against Crossref · corpus check 2026-06-10

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