Research
Mixed
Ageing is not a genetically programmed process but results from the lifelong accumulation of somatic damage due to evolutionarily optimized, limited investments in maintenance and repair systems.
Focus on maintaining health and minimizing damage (through diet, exercise, and avoiding toxins) rather than seeking a 'genetic fix' for ageing. Your body's repair systems are limited by evolutionary trade-offs, so supporting them with a healthy lifestyle is the most effective strategy for longevity.
StrongRefutesHIGH confidence
Ageing is not programmed but results from accumulation of somatic damage, owing to limited investments in maintenance and repair.
Why this rating
This is a theoretical review paper synthesizing evolutionary biology, genetics, and physiology; it is not a primary clinical trial.
Source
Understanding ageing from an evolutionary perspective
Tom Kirkwood · Journal of Internal Medicine · 2008
DOI 10.1111/j.1365-2796.2007.01901.x
narrative_reviewCited 181×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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