Research
Micronutrients & recovery
Reduced glutathione (GSH) levels in serum are increased by Lactobacilli supplementation and mediate the improvement of hepatic mitochondrial function and systemic glucose metabolism.
Lactobacilli supplementation increases serum glutathione, a key antioxidant. This increase helps protect liver mitochondria from damage caused by high sugar/fat diets, thereby improving blood sugar control. This highlights the importance of antioxidant pathways in metabolic health.
GoodSupportsHIGH confidence
Metabolomics analyses revealed that reduced glutathione may mediate these effects.
Why this rating
Supported by multi-omic network analysis, metabolomics, and in vitro cell culture experiments.
Source
Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes
Richard R. Rodrigues et al. · Nature Communications · 2021
mechanism_onlyCited 172×
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