Research
Energy balance
Reductions in insulin resistance (HOMA-IR), inflammation (CRP), and caloric/macronutrient intake are associated with cognitive improvements in MCI patients.
Improving your diet by reducing calories, carbs, and fats not only helps you lose weight but also lowers inflammation and insulin resistance, which may further support your memory and thinking skills.
GoodSupportsMEDIUM confidence
Changes in HOMA-IR, C-reactive protein, leptin and intake of energy, carbohydrates and fats were associated with improvement in cognitive tests.
Why this rating
Correlational analysis from the same trial.
Source
Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment
Nídia Celeste Horie et al. · The Journal of Clinical Endocrinology & Metabolism · 2015
DOI 10.1210/jc.2015-2315
rct · n=80Cited 166×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intentional weight loss via caloric restriction in obese elderly individuals with mild cognitive impairment (MCI) is associated with improvements in global cognition, verbal memory, executive function, and language.Good
- The cognitive benefits of weight loss are stronger in younger seniors (under 70) for memory/fluency and in APOE4 carriers for executive function.Good
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