Mixed
A 12-week combined resistance exercise and protein supplementation intervention significantly increases lean body mass in community-dwelling older adults aged 75 and younger, but not in those older than 75.
If you are 75 or younger, this combined exercise and protein strategy is effective for adding muscle mass. If you are over 75, you may not gain significant muscle mass, but you will still gain significant strength and functional ability, so the intervention remains valuable for mobility.
A significant interaction effect including age was found on lean body mass (β = −0.8; 95% CI: −1.5, −0.2), favoring participants aged 75 years and younger... The increase in lean body mass for participants aged 75 years and younger was 0.9 kg (95% CI: 0.5, 1.4) and the increase in participants older than 75 years was 0.1 kg (95% CI: −0.4, 0.6).
Why this rating
Randomized controlled trial with subgroup analysis; however, the post-hoc nature of the subgroup analysis and the small effect size in the older group reduce certainty for that specific demographic.
Source
In-Depth Analyses of the Effects of a Diet and Resistance Exercise Intervention in Older Adults: Who Benefits Most From ProMuscle in Practice?
Berber G. Dorhout et al. · The Journals of Gerontology Series A · 2021
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