Macro partitioning
High carbohydrate intake is associated with increased total mortality, while high intake of total fat and individual types of fat is associated with reduced total mortality.
Focus on the quality of your macronutrients. Instead of strictly limiting fat, ensure your fats come from unsaturated sources (like oils, nuts, fish) and moderate your carbohydrate intake, particularly refined carbs, as high carbohydrate intake has been linked to higher mortality in large global studies.
The Prospective Urban Rural (PURE) study... reported that high carbohydrate intake was associated with an increased risk of total mortality, whereas high intake of total fat and individual types of fat were associated with reduced total mortality.
Why this rating
Based on a large prospective cohort study (PURE), but subject to observational limitations and measurement error debates.
Source
Associations of fats and carbohydrates with cardiovascular disease and mortality—PURE and simple?
Xi‐Peng Cao et al. · The Lancet · 2018
DOI 10.1016/s0140-6736(18)30793-1
More from this paper
- Food Frequency Questionnaires (FFQs) are error-prone for estimating fat intake, particularly for edible oils in Chinese populations, leading to potential inaccuracies in the PURE study's conclusions.Good
- Body Mass Index (BMI) is a major confounder in studies linking macronutrient intake to mortality, and its exclusion from multivariate analysis in the PURE study is questionable.Good
Related findings · Macro partitioning
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- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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