Research
Adherence
Food Frequency Questionnaires (FFQs) are error-prone for estimating fat intake, particularly for edible oils in Chinese populations, leading to potential inaccuracies in the PURE study's conclusions.
Be cautious when interpreting dietary studies that rely solely on self-reported food frequency questionnaires, especially for fat intake. For more accurate assessment, biomarkers like erythrocyte membrane fatty acids are superior.
GoodQualifiesHIGH confidence
using questionnaires to infer the amount, quality, and composition of intake of fats is error prone because of the complexity of foods and the possibility of implausible questionnaire entries.
Why this rating
Based on methodological critique and comparison with other surveys (CHNS).
Source
Associations of fats and carbohydrates with cardiovascular disease and mortality—PURE and simple?
Xi‐Peng Cao et al. · The Lancet · 2018
DOI 10.1016/s0140-6736(18)30793-1
narrative_reviewCited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Body Mass Index (BMI) is a major confounder in studies linking macronutrient intake to mortality, and its exclusion from multivariate analysis in the PURE study is questionable.Good
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