Energy balance
Sustained weight loss of at least 5% is recommended for individuals with overweight or obesity at moderate atherosclerotic cardiovascular disease (ASCVD) risk to reduce cardiometabolic risk factors and delay type 2 diabetes onset.
If you are at moderate cardiovascular risk, aim to lose just 5% of your body weight through a daily calorie deficit of 500-750 calories and 150 minutes of weekly exercise. This modest loss is scientifically proven to significantly lower your blood pressure, improve cholesterol, and drastically reduce your risk of developing type 2 diabetes.
Sustained weight reduction of at least 5% is RECOMMENDED in individuals with overweight or obesity at MODERATE ASCVD RISK to reduce CV risk factors, such as hypertension and dyslipidaemia, and to delay or prevent type 2 diabetes onset.
Why this rating
Based on multiple RCTs (DPP, Look AHEAD) and meta-analyses with low heterogeneity.
Source
2025 Brazilian evidence-based guideline on the management of obesity and prevention of cardiovascular disease and obesity-associated complications: a position statement by five medical societies
Cynthia Melissa Valério et al. · Diabetology & Metabolic Syndrome · 2025
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