Research
Mixed
The association between SFA intake and dyslipidemia is modified by LDL-C-related genetic polymorphisms, specifically rs6102059.
Genetic testing for LDL-C-related polymorphisms like rs6102059 may help identify Filipino women who are particularly sensitive to the dyslipidemia risks of high SFA intake. Those with CC alleles should be especially cautious with saturated fat intake.
ModerateQualifiesMEDIUM confidence
When we examined the interaction by LDL-C-related polymorphisms, the association with dyslipidemia was more pronounced among participants with CC alleles than among those with T alleles of rs6102059 (P for interaction = 0.01).
Why this rating
Observational study with genetic interaction analysis; requires replication.
Source
Associations of Dietary Intakes of Total and Specific Types of Fat with Blood Lipid Levels in the Filipino Women’s Diet and Health Study (FiLWHEL)
Heejin Lee et al. · Global Heart · 2023
DOI 10.5334/gh.1209
cross_sectional · n=406Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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