Research
Energy balance
Three years of treatment with tirzepatide resulted in substantial and sustained weight reduction and a markedly lower risk of progression to type 2 diabetes than that with placebo.
Tirzepatide is effective for long-term weight management and diabetes prevention.
StrongSupportsmedium confidence
Three years of treatment with tirzepatide in persons with obesity and prediabetes resulted in substantial and sustained weight reduction and a markedly lower risk of progression to type 2 diabetes than that with placebo.
Why this rating
Based on a large randomized controlled trial.
Source
Tirzepatide for Obesity Treatment and Diabetes Prevention
Ania M. Jastreboff et al. · New England Journal of Medicine · 2024
rct · n=2539Cited 359×
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