Research
Hormonal
The proportion of participants discontinuing treatment for any reason was lower with semaglutide (13.5%) compared to liraglutide (27.6%).
Semaglutide may lead to better treatment adherence compared to liraglutide.
StrongSupportsmedium confidence
Proportions of participants discontinuing treatment for any reason were 13.5% with semaglutide and 27.6% with liraglutide.
Why this rating
Based on a randomized, open-label, phase 3b trial design.
Source
Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes
Domenica M. Rubino et al. · JAMA · 2022
rct · n=338Cited 856×
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