Research
Energy balance
Participants had significantly greater odds of achieving 10% or more weight loss with semaglutide compared to liraglutide (70.9% vs 25.6%).
Semaglutide may offer a higher likelihood of significant weight loss compared to liraglutide.
StrongSupportsmedium confidence
Participants had significantly greater odds of achieving 10% or more...with semaglutide vs liraglutide (70.9% of participants vs 25.6%).
Why this rating
Based on a randomized, open-label, phase 3b trial design.
Source
Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes
Domenica M. Rubino et al. · JAMA · 2022
rct · n=338Cited 856×
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