Research
Energy balance
Calorie restriction (CR) results in a significant decrease in body weight of -7.5±0.4 kg compared to a control group with a change of 0.1±0.5 kg after 24 months.
Practitioners can consider CR as an effective method for weight loss in non-obese adults.
StrongSupportsmedium confidence
There were significant decreases in body weight (‐7.5±0.4 vs. 0.1±0.5 kg) in the CR group compared to the AL group at 24 months (all p<0.001).
Why this rating
Based on the randomized clinical trial design.
Source
Body composition changes with calorie restriction: results from the CALERIE trial (371.6)
Sai Krupa Das et al. · The FASEB Journal · 2014
DOI 10.1096/fasebj.28.1_supplement.371.6
rct · n=218
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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