Research
Energy balance
In Chinese adults with overweight or obesity, once-weekly mazdutide at a dose of 4 mg for 32 weeks led to a mean percentage change in body weight from baseline of -10.09%.
Mazdutide may be an effective treatment option for weight loss in adults with obesity or overweight.
StrongSupportsmedium confidence
At week 32, the mean percentage change in body weight from baseline was -10.09% (95% confidence interval [CI], -11.15 to -9.04) in the 4-mg mazdutide group.
Why this rating
Based on a phase 3, double-blind, placebo-controlled trial.
Source
Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight
Linong Ji et al. · New England Journal of Medicine · 2025
rct · n=610Cited 64×
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