Research
Energy balance
In the 6-mg mazdutide group, the mean percentage change in body weight from baseline at week 32 was -12.55%.
Higher doses of mazdutide may lead to greater weight loss in adults with obesity or overweight.
StrongSupportsmedium confidence
At week 32, the mean percentage change in body weight from baseline was -12.55% (95% CI, -13.64 to -11.45) in the 6-mg mazdutide group.
Why this rating
Based on a phase 3, double-blind, placebo-controlled trial.
Source
Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight
Linong Ji et al. · New England Journal of Medicine · 2025
rct · n=610Cited 64×
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