Research
Energy balance
Efsubaglutide Alfa produced a mean weight reduction of 7.16% versus 0.86% with placebo.
Efsubaglutide Alfa may be an effective treatment option for weight loss in individuals with obesity or overweight.
StrongSupportsmedium confidence
Efsubaglutide Alfa produced a mean weight reduction of 7.16% (95% CI: -8.08 to -6.24) versus 0.86% with placebo.
Why this rating
Based on the randomized, double-blind, placebo-controlled trial design.
Source
Efficacy, tolerability, and safety of Efsubaglutide Alfa in participants with obesity or overweight ( <scp>LIGHT</scp> 1): A randomized, double‐blind, placebo‐controlled, ascending‐dose phase 2a trial
Fei Gao et al. · Diabetes Obesity and Metabolism · 2026
rct · n=50
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