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82.5% of Efsubaglutide-treated participants achieved ≥5% weight loss.

A significant proportion of individuals treated with Efsubaglutide Alfa can expect to achieve clinically meaningful weight loss.

StrongSupportsmedium confidence
Overall, 82.5% of Efsubaglutide-treated participants achieved ≥5% weight loss (vs. 0% placebo).
Fei Gao et al. · Diabetes Obesity and Metabolism · 2026

Why this rating

Based on the randomized, double-blind, placebo-controlled trial design.

Source

Efficacy, tolerability, and safety of Efsubaglutide Alfa in participants with obesity or overweight ( <scp>LIGHT</scp> 1): A randomized, double‐blind, placebo‐controlled, ascending‐dose phase 2a trial

Fei Gao et al. · Diabetes Obesity and Metabolism · 2026

rct · n=50
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