Research
Metabolic adaptation
Dietary intake of marine omega-3 PUFAs and replacing SFAs with plant MUFAs or linoleic acid were associated with lower total, CVD, and certain cause-specific mortality.
Incorporating these fats into the diet may reduce mortality risk.
StrongSupportsmedium confidence
Dietary intake of marine omega-3 PUFAs and replacing SFAs with plant MUFAs or linoleic acid were associated with lower total, CVD, and certain cause-specific mortality.
Why this rating
Based on the large prospective cohort study design.
Source
Dietary Fats in Relation to Total and Cause-Specific Mortality in a Prospective Cohort of 521 120 Individuals With 16 Years of Follow-Up
Pan Zhuang et al. · Circulation Research · 2019
DOI 10.1161/circresaha.118.314038
cohort · n=521120Cited 155×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intakes of saturated fatty acids (SFAs), trans-fatty acids, animal monounsaturated fatty acids (MUFAs), α-linolenic acid, and arachidonic acid were associated with higher mortality.Strong
- Isocalorically replacing 5% of the energy from SFAs with plant MUFAs was associated with 15%, 10%, 11%, and 30% lower total mortality, CVD, cancer, and respiratory disease mortality, respectively.Strong
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