Research
Metabolic adaptation
Cases of metabolic dysfunction-associated steatohepatitis (MASH) are expected to rise from 14.9 million (5.8% of US adults) in 2020 to 23.2 million (7.9% of US adults) by 2050.
Increased awareness and management strategies for MASH are needed.
StrongSupportsmedium confidence
Cases of MASH would increase from 14.9 million (5.8% of US adults) in 2020 to 23.2 million (7.9% of US adults) by 2050.
Why this rating
Based on a decision analytical modeling study design.
Source
Estimated Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease in US Adults, 2020 to 2050
Phuc Le et al. · JAMA Network Open · 2025
other · n=2821624Cited 165×
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