Research
Metabolic adaptation
Liver-related mortality is estimated to increase from 30,500 deaths (1.0% of all-cause deaths in adults) in 2020 to 95,300 deaths (2.4%) in 2050.
Strategies to reduce liver-related mortality must be prioritized.
StrongSupportsmedium confidence
Liver-related mortality was estimated to increase from 30 500 deaths (1.0% of all-cause deaths in adults) in 2020 to 95 300 deaths (2.4%) in 2050.
Why this rating
Based on a decision analytical modeling study design.
Source
Estimated Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease in US Adults, 2020 to 2050
Phuc Le et al. · JAMA Network Open · 2025
other · n=2821624Cited 165×
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