Research
Metabolic adaptation
After substantial weight loss (12.7 +/- 2 kg), metabolic parameters improved further, with the effect of weight loss approximately equal to that obtained with initial calorie restriction.
Weight loss is equally important as calorie restriction for improving metabolic health in obese NIDDM patients.
StrongSupportsmedium confidence
After a substantial weight loss (12.7 +/- 2 kg), each parameter improved further, with the effect of weight loss approximately equal to that obtained with initial calorie restriction.
Why this rating
Based on the controlled study design involving direct measurements.
Source
Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus.
David E. Kelley et al. · The Journal of Clinical Endocrinology & Metabolism · 1993
other · n=7Cited 122×
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