Research
Energy balance
Participants who sat for 8 or more hours per day experienced a 17% to 50% higher associated risk of the composite outcome across physical activity levels.
Encouraging reduced sitting time is crucial, even for those who are physically active.
StrongSupportsmedium confidence
Compared with those who reported sitting time less than 4 hours per day and high physical activity level, participants who sat for 8 or more hours per day experienced a 17% to 50% higher associated risk of the composite outcome across physical activity levels.
Why this rating
Based on the large cohort study design.
Source
Association of Sitting Time With Mortality and Cardiovascular Events in High-Income, Middle-Income, and Low-Income Countries
Sidong Li et al. · JAMA Cardiology · 2022
DOI 10.1001/jamacardio.2022.1581
cohort · n=105677Cited 128×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Higher sitting time (≥8 hours per day) is associated with an increased risk of all-cause mortality (HR, 1.20; 95% CI, 1.10-1.31) and major cardiovascular disease (HR, 1.21; 95% CI, 1.10-1.34).Strong
- The association of sitting time with the composite outcome is stronger in low-income and lower-middle-income countries (HR, 1.29; 95% CI, 1.16-1.44) compared to high-income and upper-middle-income countries (HR, 1.08; 95% CI, 0.98-1.19).Strong
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