Research
Energy balance
The two diet groups did not differ significantly in high-density lipoprotein cholesterol and triglyceride levels.
Practitioners can note that while total and LDL cholesterol improved, HDL and triglycerides remained stable across both diets.
StrongSupportsmedium confidence
The 2 diet groups did not differ significantly in high-density lipoprotein cholesterol and triglyceride levels.
Why this rating
Based on the randomized clinical trial design.
Source
The Effect of a Plant-Based Diet on Plasma Lipids in Hypercholesterolemic Adults
Christopher D. Gardner et al. · Annals of Internal Medicine · 2005
DOI 10.7326/0003-4819-142-9-200505030-00007
rct · n=120Cited 118×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- The Low-Fat Plus diet resulted in a greater reduction in total cholesterol compared to the Low-Fat diet, with changes of -0.46 mmol/L (-17.6 mg/dL) versus -0.24 mmol/L (-9.2 mg/dL) respectively (P = 0.01).Strong
- The Low-Fat Plus diet led to a greater reduction in LDL cholesterol compared to the Low-Fat diet, with changes of -0.36 mmol/L (-13.8 mg/dL) versus -0.18 mmol/L (-7.0 mg/dL) respectively (P = 0.02).Strong
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →