Hormonal
In patients with new-onset type 2 diabetes, a weight gain of 10% or more within the first two years is associated with an increased risk of stroke.
If you have recently been diagnosed with type 2 diabetes, try to avoid gaining more than 10% of your body weight in the first two years. Significant weight gain is linked to a higher risk of stroke. Maintaining a stable weight is associated with the lowest risk of cardiovascular events and mortality.
Subjects with weight gain ≥ + 10% had a significantly higher risk of stroke (HR 1.51, 95% CI 1.23–1.84) compared with the group with stable weight.
Why this rating
Large cohort, robust statistical adjustment, but observational nature prevents causal confirmation.
Source
Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study
Mee Kyoung Kim et al. · Cardiovascular Diabetology · 2019
DOI 10.1186/s12933-019-0838-9
More from this paper
- In patients with new-onset type 2 diabetes, a weight loss of 10% or more within the first two years is associated with the highest risk of all-cause mortality.Good
- In patients with new-onset type 2 diabetes, weight change (gain or loss) of more than 10% is associated with higher all-cause mortality compared to stable weight.Good
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