Research

Metabolic adaptation

NAC pretreatment dampens acute episodes of oxidative stress through reversible perturbations in global metabolism.

NAC could be used as a preventive measure against oxidative stress during intense physical activity.

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Our work demonstrates the proof-of-principle that NAC pretreatment is effective at dampening acute episodes of oxidative stress by reversible perturbations in global metabolism.
Richard Lee et al. · Analytical Chemistry · 2010

Why this rating

Based on the experimental design and outcomes described.

Source

Differential Metabolomics for Quantitative Assessment of Oxidative Stress with Strenuous Exercise and Nutritional Intervention: Thiol-Specific Regulation of Cellular Metabolism with <i>N</i>-Acetyl-<scp>l</scp>-Cysteine Pretreatment

Richard Lee et al. · Analytical Chemistry · 2010

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